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Accelerometer-Derived “Weekend Warrior” Physical Activity Pattern and Venous Thromboembolism Incidence and Mortality: A Prospective Cohort Study

A prospective UK Biobank study of accelerometer-measured weekend-warrior activity and the incidence of venous thromboembolism and mortality among people with existing VTE.

Research question

Is concentrating recommended moderate-to-vigorous physical activity into one or two days per week associated with venous thromboembolism (VTE) incidence and survival?

Study

This prospective UK Biobank analysis used wrist-accelerometer data from 92,392 participants without VTE to study incident disease and from 3,019 participants with prevalent VTE to study mortality. Activity patterns were classified as inactive, regularly active, or weekend warrior.

Key finding

Over a median 11.1-year follow-up, the weekend-warrior pattern was associated with lower incident VTE than inactivity (HR 0.813, 95% CI 0.733–0.902) and with lower all-cause mortality among participants with prevalent VTE (HR 0.567, 95% CI 0.438–0.734). Risks did not differ significantly from those of regularly active participants.

Authorship

First author.

Publication

Journal of the American Heart Association · 2026

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Publication record

Article details

  1. Published in the Journal of the American Heart Association

    First-author article. DOI